Research and Publications

Numerous international awards and accolades conferred upon Dato' Dr. T. K. Ho speaks impressively of his dedicated and comprehensive  research in the realm of medicine that he specializes in. Dato' Dr. Ho has written and  published several books on vascular surgery, many which are international peer-reviewed journals. The medical fraternity relished the  distinct privilege of Dato' Dr. Ho's  achievements where his papers had been presented at numerous internatIonal vascular meetings such as the Vascular Surgery of Great Britain & Ireland (VSGBI) Annual Meeting.

PUBLICATIONS & PRESENTATIONS TO LEARNED SOCIETIES

    PEER REVIEWED PUBLICATIONS
  1. Wan Naimah Wan Ab Naima, Poo Balan Ganesanb, Zhonghua Sunc, Jing Leid, Shirley Jansene, Shahrul Amry Hashimh, Teik Kok Ho, Einly Lim. Flow Pattern Analysis in Type B Aortic Dissection Patients After Stent–Grafting Repair: Comparison between complete and incomplete false lumen thrombosis; International Journal For Numerical Methods in Biomedical Engineering, March 2018. Article DOI: https://doi.org/10.1002/cnm.2961
  2. Hart CA, Tsui J, Khan K, Ho TK, Shiwen X, Ponticos M, Abraham DJ, Baker DM. Critical limb ischaemia in adult human skeletal muscle increases satellite cell proliferation but not differentiation. Surgical Science, May 2015; 6(5) 198-207
  3. TK Ho, RD Leigh, J Tsui; Diabetic Foot Disease and Oedema; British Journal of Diabetes and Vascular Disease, Jan/Feb 2013; 13(1):45-50
  4. TK Ho and DM Baker; Appraisal and Revalidation; Surgery Journal; Sept 2012 30(9):447-454
  5. J Berwin, TK Ho and R D’Souza; Small Bowel evisceration through the anus - report of a case and review of literature; BMJ Case Report, May 8;2012. pii: bcr1220115316 2012
  6. Teik K Ho, X Shiwen, D Abraham, J Tsui, D Baker; Stromal cell derived factor 1 (SDF-1) / CXCL12 as potential target of therapeutic angiogenesis in critical leg ischaemia. Cardiology Research and Practice, vol 2012, Article ID 143209, 7 pages, 2012. doi: 10.1155/2012/143209, 2012
  7. TK Ho; Book review; Journal of the Association of Surgeons of Great Britain and Ireland; March 2012; Number 36
  8. TK Ho, DM Baker; Chapter 2 Complications related to cardio-respiratory morbidity; Complications in Vascular and Endovascular Surgery 1st Edition, 2011
  9. TK Ho and Werner Luttmann; Invited Mini Review Angiogenic effects of SDF-1/CXCL12 variants; Modern Aspects in Biomedicine 2, 2010
  10. D Joshi, J Tsui, TK Ho, S Selvakumar, DJ Abraham, DM Baker; Review Of The Role Of Erythropoietin In Critical Leg Ischemia; Angiology; Aug 2010; 61(6):541-50
  11. TK Ho, S Xu, P Leoni, DJ Abraham, DM Baker; Angiogenic Effects of Stromal cell-Derived Factor-1 (SDF-1/CXCL12) Variants In-vitro and the In-vivo Expressions of CXCL12 Variants and CXCR4 in Human Critical Leg Ischemia; Journal of Vascular Surgery; March 2010 ; 51(3):689-99
  12. Matharu, Balpreet; Khalid, Usman; Ho, Teik; Patel, Kaushik; Bloom, Ian. A case report: “An unsuspected case of acute mesenteric ischaemia” BMJ Case Report, April 7; 2009: bcr10.2008.1065
  13. TK Ho; Prevention and management of deep vein thrombosis. Primary Care of Vascular Disease 2nd Edition, 2007
  14. TK Ho, DJ Abraham, CM Black, DM Baker; Hypoxia-inducible factor 1 in lower limb ischemia. Vascular Nov-Dec 2006; 14(6):321-7.
  15. TK Ho, V Rajkumar, CM Black, DJ Abraham, DM Baker; Increased angiogenic response but deficient arteriolization and abnormal microvessel ultrastructure in critical leg ischaemia. Br J Surg. Nov 2006; 93(11):1368-76.
  16. Teik K Ho, Vineeth Rajkumar, Carol M Black, David J Abraham, Daryll M Baker, The increased endogenous angiogenic response and hypoxia inducible factor – 1expressionin human critical limb ischemia. Journal of Vascular Surgery; January 2006 43(1):125-33.
  17. TK Ho, V Rajkumar, CM Black, DJ Abraham, DM Baker, Critical limb ischemia classification and therapeutic angiogenesis. International Journal of Angiology; May 2005; 14(2):49-59
    PUBLISHED ABSTRACTS
  1. M Salji, P Gogalniceanu, TK Ho, S Mackenzie, P Patient, S Choksy, C Backhouse, R Motson, A Howard; Comparison of operative outcomes of laparoscopic versus open repair of abdominal aortic aneurysms – A prospective study of a single centre learning experience. International Journal of Surgery 2012; 10(8):S109
  2. T. K. Ho, S. Xu, D. Joshi, J. Tsui, D. J. Abraham,D. M. Baker. CXCL12 upregulated by hypoxia and stimulates cell proliferation via P44/42 and attenuates apoptosis via PI3/AKT pathways in angiogenesis. British Journal of Surgery 97(S6) 13-14 Nov 2010
  3. Dhiraj Joshi, T. K. Ho, Janice Tsui, S. Selvakumar, Korsa Khan, David Abraham, Daryll Baker. Erythropoietin is angiogenic and tissue protective in human critical limb ischaemia. British Journal of Surgery 97(S6) 13-14 Nov 2010
  4. T. K. Ho The Angiogenic Effects of CXCL12 Variants and the Expressions of CXCL12 Variants and CXCR4 in Human Critical Limb Ischaemia. Cardiovascular Pathology; Vol 17(4) Page 268; July/August 2008
  5. T. K. Ho, S. Xu, P. Leoni, N. Aden, C. DiSalvo, R.Walesby, C.M. Black, D.J. Abraham, G. Hamilton, D.M. Baker. Increased SDF-1alpha and CXCR4 but not SDF-1beta expression in human critical limb ischaemia. British Journal of Surgery; Vol 95(4) S1:3; February 2008
  6. T. K. Ho, M. Griffiths, M. Dashwood, R. Stratton, C. M. Black, D.J. Abraham, G. Hamilton and D.M. Baker. Endothelin-1 promotes proliferation and angiogenesis via the ETB receptor. British Journal of Surgery; Vol 94 S1:2; February 2007
  7. T.K. Ho, M. Griffiths, R. Stratton, C.M. Black, D.J. Abraham and D.M. Baker. Endothelin-1 promotes proliferation and angiogenesis in cultured endothelial cells via the ETB receptor Vascular Pharmacology; Vol 45(3) Page e114 September 2006
  8. T.K. Ho, X. Shiwen, C. DiSalvo, R.K. Walesby, C.M. Black, D.J. Abraham and D.M. Baker. Angiogenic roles of stromal-derived factor-1(SDF-1/CXCL12) variants and in-vivo CXCR4 expression in microvessels of human critical limb ischaemia. Vascular Pharmacology; Vol 45(3) Page e116; September 2006
  9. T.K. Ho, V. Rajkumar, K. Khan, C. DiSalvo, R.K. Walesby, C.M. Black, D.J. Abraham and D.M. Baker. Increased angiogenic response but deficient arteriolization and abnormal microvessel ultrastructure in human critical limb ischaemia. Vascular Pharmacology; Vol 45(3) Page e118; September 2006
  10. TK Ho, S Xu, DJ Abraham, CM Black, DM Baker. Angiogenic roles of the chemokine stromal-derived factor-1(SDF-1/CXCL12) variants and involvement of AKT and ERK1/2 signalling pathways in human microvascular endothelial cells. British Journal of Surgery Vol 9(7):896-902 July 2006
  11. TK Ho, V Rajkumar, M Ponticos, M Garcia, K Khan, C Hart, DiSalvo, RK Walesby, DJ Abraham, CM Black, DM Baker. Increased hypoxia inducible factor-1alpha and localisation of erythropoietin in human critical limb ischaemia. British Journal of Surgery Vol 9(7):896-902 July 2006
  12. TK Ho, V Rajkumar, M Ponticos, M Garcia, K Khan, C Hart, DiSalvo, RK Walesby, DJ Abraham, CM Black, DM Baker. Increased hypoxia inducible factor-1alpha and localisation of erythropoietin in human critical limb ischaemia British Journal of Surgery Vol 93 (S2):21 April 2006
  13. TK Ho, S Xu, DJ Abraham, CM Black, DM Baker. The chemokine stromal-derived factor-1 (SDF-1/CXCL12) beta is the more potent variant in human microvascular cell survival and proliferation. British Journal of Surgery Vol 93 (S2):8 April 2006
  14. TK Ho, DJ Abraham, CM Black, V Rajkumar, C DiSalvo, RK Walesby, C Hart, DM Baker, Increased hypoxia inducible factor – 1alpha expression and angiogenesis in critical limb ischaemia in human. British Journal of Surgery Vol 92 (S1):81 April 2005
    ORAL PRESENTATIONS:
  1. A Dedicated Multidisciplinary Amputee Service Achieves Improved Patient Experience and Reduces Length of Stay. The Vascular Society of Great Britain and Ireland (VSGBI) Annual Meeting, Edinburgh, November 2011
  2. CXCL12 Upregulated By Hypoxia And Stimulates Cell Proliferation Via p44/42 And Attenuates Apoptosis Via PI3/Akt Pathways In Angiogenesis, Society of Academic and Research Surgery (SARS) Annual Meeting, London, January 2010
  3. The Angiogenic Effects of CXCL12Variants and the Expressions of CXCL12 Variants and CXCR4 in Human Critical Limb Ischaemia, International Society of Applied Cardiovascular Biology (ISCAB) Biennial Meeting, Bordeaux, September 2008 – Young Investigator Award Winner
  4. Increased SDF-1alpha and CXCR4 but not SDF-1beta expression in human critical limb ischaemia, SARS Annual Meeting, Birmingham, January 2008
  5. Stromal-derived factor (SDF)-1 in Human Critical Limb Ischaemia, The Vascular Society of Great Britain and Ireland (VSGBI) Annual Meeting, Manchester, November 2007 – Prize Winner of SARS Session
  6. Increased SDF-1alpha But Not SDF-1beta Expression With Raised CXCR4 In Human Critical Limb Ischemia, Society of Vascular Surgery (SVS) Research Initiatives Conference, Washington DC, March 2007
  7. Endothelin-1 promotes proliferation and angiogenesis via the ETB receptor, The Vascular Society of Great Britain and Ireland (VSGBI) Annual Meeting, Edinburgh, November 2006
  8. Angiogenic Effects Of Stromal-derived Factor-1(SDF-1/CXCL12) Variants And In-vivo Microvessel Expression Of CXCR4 In Human Critical Limb Ischemia; Society of Vascular Surgery (SVS) Research Initiatives Conference, Washington DC, March 2006
  9. Patey Prize Session: Increased Hypoxia Inducible Factor – 1 And Localisation Of Erythropoietin In Human Critical Limb Ischaemia, Society of Academic and Research Surgery (SARS) Meeting, Edinburgh, January 2006
  10. Patey Prize Session: Angiogenic Roles Of The Chemokine Stromal-Derived Factor-1 (SDF-1/CXCL12) Variants And Involvement Of Akt And Erk 1/2 Signalling Pathways In Human Microvascular Endothelial Cells, Society of Academic and Research Surgery (SARS) Meeting, Edinburgh, January 2006
  11. BJS Prize Session: Increased HIF-1alpha and Localisation of Erythropoietin In Human Critical Limb Ischaemia, The Vascular Society of Great Britain and Ireland (VSGBI) Annual Meeting, Bournemouth, November 2005
  12. The Chemokine SDF-1(CXCL12)-beta is The More Potent Variant In Human Microvascular Cell Survival and Proliferation, VSGBI Annual Meeting, Bournemouth, November 2005
  13. International Union of Angiology Prize Session: Angiogenesis and Characterisation of Vascular Endothelial Subtypes in Human Critical Limb Ischaemia, EUROCHAP, Glasgow, October 2005
  14. Increased Angiogenic Response and HIF-1alpha in Human Critical Limb Ischaemia; Society of Vascular Surgery (SVS) Annual Meeting, Chicago, USA, June 2005
    POSTERS:
  1. Endothelin-1 promotes proliferation and angiogenesis in cultured endothelial cells via the ETB receptor; International Vascular Biology Meeting (IVBM), Noordwijkerhout, The Netherlands, June 2006
  2. Increased Angiogenic Response But Deficient Arteriolization And Abnormal Microvessel Ultrastructure In Human Critical Limb Ischaemia; IVBM, Noordwijkerhout, The Netherlands, June 2006
  3. Angiogenic Roles Of Stromal-Derived Factor-1(SDF-1/CXCL12) Variants and In-vivo CXCR4 Expression in Microvessels of Human Critical Limb Ischaemia; IVBM, Noordwijkerhout, The Netherlands, June 2006
  4. Endothelin-1 Promotes Proliferation and Angiogenesis in Cultured Endothelial Cells via The ETB Receptor, SVS Research Initiatives Conference, Washington DC, March 2006
  5. Increased HIF-1alpha and Angiogenic Response In Critical Limb Ischaemia In Human; Association of Surgeons of Great Britain & Ireland (ASGBI) Annual Meeting, Glasgow, April 2005
  6. Endogenous Angiogenic Response In Human Critical Limb Ischaemia; Association of Surgeons in Training (ASiT) Annual Meeting, Sheffield March 2005
  7. Unscheduled Re-Attendence In The A&E Department; British Association for Emergency Medicine (BAEM) Conference, April 2003